USS Abeona was a mercantile stern wheel steamer that traded on the Mississippi between 1831 and her destruction by fire in 1872, except for two years, between 1863 and 1865, when she served the United States Navy as a gunboat.

Abeona was built in 1831, at Pittsburgh, Pennsylvania, and the US Navy purchased her on 21 December 1864, at Cincinnati, Ohio.

The navy converted her to a "tinclad" gunboat at Mound City, Illinois, and commissioned her there on 10 April 1865, (one day after the surrender of General Robert E.

After all organized Confederate resistance ceased and the South had begun its painful and uncertain return to a peaceful way of life, Abeona was decommissioned at Mound City, 4 August 1865.

The veteran stern wheeler operated on the Mississippi, and its branches, until she caught fire at Cincinnati, 7 March 1872, and was destroyed.