She was then laid up at Boston Navy Yard until joining the West Indies Squadron in 1836.
Except for two short periods in ordinary at New York Navy Yard she served continuously for the next 10 years.
She was then ordered to join Commodore Conner's Home Squadron blockading the Mexican east coast.
While en route to her new station, Boston was wrecked on Eleuthera Island, Bahamas, during a squall on 15 November 1846.
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