USS Clifton was a shallow-draft side-wheel paddle steamer, built in 1861 at Brooklyn, as a civilian ferry.

In April she towed mortar schooners into the Mississippi River and supported them as they bombarded the Confederate fortifications below New Orleans.

Following the fall of the forts and city later in the month, she operated with Rear Admiral David Farragut's squadron during its drive up the river to Vicksburg, Mississippi.

On 8 September 1863, during a Union attack on Sabine Pass, Texas, Clifton grounded while under intense cannon fire and was captured.

After attempts to refloat the ship failed, Clifton was burned by her crew to prevent capture by Union warships.