The second USS Comfort (AH-6) was launched 18 March 1943 by Consolidated Steel Corporation, Wilmington, Los Angeles, under a Maritime Commission contract; sponsored by First Lieutenant E. Hatchitt, USAMC; transferred to the Navy the same day; converted to a hospital ship by Bethlehem Steel Co., San Pedro, Calif.; and commissioned 5 May 1944.

The Army medical complement table of organization provided for the temporary reinforcement of the staff if the ship directly supported amphibious operations.

Following a voyage to Subic Bay and Lingayen Gulf, Luzon, for evacuees in March, the hospital ship stood by off Okinawa from 2 to 9 April, receiving wounded for evacuation to Guam.

She made another voyage to Manila, Yokohama, Inchon, Korea, and Okinawa between 1 January and 4 March 1946 before being decommissioned at San Francisco on 19 April 1946.

This focused on the United States Navy Nurse Corps in World War II during the Battle of Iwo Jima.