Departing San Francisco, California, on 25 May 1944, Crowley arrived at Pearl Harbor on 31 May and joined in anti-submarine training exercises in Hawaii until 12 August.

Between 15 September and 18 November 1944, Crowley sailed out of Manus escorting shipping to the Palau Islands during the invasion and consolidation, with occasional voyages to Humboldt Bay, New Guinea, and the Solomons.

On 26 September she joined Donaldson (DE-44) in giving assistance to the merchant ship SS Don Marquis rescuing her survivors and bringing her fires under control to save her war cargo.

Crowley based at Ulithi from 21 November 1944, joining a logistics group supporting the fast carrier task forces.

Departing Ulithi on 22 March, Crowley arrived at Guam on 9 April and continued escorting oilers during the Okinawa operations until 18 June.