USS Doyle (FFG-39) was the 30th ship to be constructed in the Oliver Hazard Perry class of guided missile frigates of the United States Navy.

From 24 February to 3 March 1987, Doyle sailed in company with guided missile cruiser Josephus Daniels (CG-27) through the Turkish Straits and carried out freedom of navigation exercises in the Black Sea.

During the fall of 1991, Doyle deployed with elements of Standing Naval Force Atlantic and embarked a CL-227 Maritime Aerial VTOL Unmanned System (MAVUS) for operational testing.

During a counter narcotics deployment to the Caribbean, 4 April – 20 June 2005, Doyle, and Cutlass 463, her embarked Sikorsky SH-60B Seahawk of Helicopter Antisubmarine Squadron (Light) (HSL) 46 Detachment 3, pursued fishing vessel Dos Continentes, suspected of smuggling cocaine, north of the Panamanian/Colombian coast, 3 May.

She lowered a rigid hull inflatable boat (RHIB) that rescued four of the smugglers, and battled the fire for several hours until they extinguished the flames during the mid watch.

The ship's damage control sailors, reinforced by Coast Guard law enforcement agents, boarded Dos Continentes and recovered several packages containing 150 pounds of cocaine from the hulk.

The frigate made a total of five interdictions during her deployment that led to the apprehension of 28 narco-terrorists, and the seizure or destruction of an estimated $315 million worth of cocaine (83 bales during the first month alone).