After coastal escort duty, Frankford made three voyages to screen convoys from the east coast to Casablanca and Northern Ireland between 27 June 1943 and 29 November.

She then returned to coastal escort, antisubmarine patrols, and duty at Norfolk training prospective crews for new construction until 18 April 1944 when she sailed from New York for Plymouth, England.

In preparation for the invasion of Normandy, Frankford escorted transports and other ships to training in Scottish waters and to the assembly points in the south of England, until 5 June, when she sortied from Plymouth for Omaha Beach.

Three days later, Frankford sailed from Plymouth to screen a group of landing craft to the Mediterranean, and on 6 August 1944, she arrived at Naples for the invasion of southern France.

Frankford served on an air-sea rescue station in the eastern Mediterranean during the President's flight out and back, and returned to New York on 27 February.