The fourth USS Gridley (DDG-101) is the 51st Arleigh Burke-class destroyer in the United States Navy.

In May 2004, the Secretary of the Navy announced the names of five new Arleigh Burke-class destroyers, including Gridley.

She has joined the Pacific Fleet and is homeported at Naval Station Everett.

Gridley departed Naval Base San Diego on 19 May 2008 for her maiden deployment and returned on 25 November 2008.

[citation needed] On 9 July 2016 Gridley arrived at her new homeport in Everett, Washington.