USS Guilford (APA-112) was a Bayfield-class attack transport in service with the United States Navy from 1945 to 1946.

She was laid down (date unknown) as a Maritime Commission type (C3-S-A2) hull under Maritime Commission contract (MCV hull 873) by the Ingalls Shipbuilding Corporation of Pascagoula, Mississippi; launched on 14 July 1944; sponsored by Mrs. Thomas Lowry Bailey, wife of the Governor of the State; converted to an attack transport by Waterman Steamship Corporation of Mobile, Alabama; and commissioned there on 14 May 1945.

Arriving on 22 June 1945 she served as a training ship for pre-commissioning crews until 30 July.

Guilford then took on board cargo and troops at Norfolk, Virginia and sailed for the Pacific via San Diego.

After off-loading troops at Iwo Jima and in the Japanese home islands, Guilford was attached to "Operation Magic Carpet" on 18 October.