USS Howorth (DD-592) was a Fletcher-class destroyer built for the United States Navy during World War II.

Later in the year, he joined Cushing's expedition up the Roanoke River to sink Confederate ram CSS Albemarle.

In his report Cushing noted: "Acting Master's Mate William L. Howorth, of the Monticello, showed, as usual conspicuous bravery."

She was laid down on 26 November 1941, launched on 10 January 1943, and commissioned on 3 April 1944 at Puget Sound Naval Shipyard in Bremerton, Washington.

The convoy arrived after seven days at sea, and Howorth remained in Hawaii until 25 August, at which point she sailed for Hollandia, along with the ammunition ship Sangay.

Howorth made several convoy trips to Kossol Roads, Guam, and Manus, before returning to the Philippines for the battle at Ormoc on 7 December 1944.

Howorth again provided fire support and anti-aircraft protection during the invasion and subsequent fighting on Iwo Jima.

On her first day off Okinawa, Howorth was moving to her station with the cruiser St. Louis and destroyer Newcomb, when she was attacked by eight kamikazes.