USS Knox (DE/FF-1052) was the lead ship of her class of destroyer escorts in the United States Navy.

The Knox-class design was derived from the Brooke-class frigate modified to extend range and without a long-range missile system.

The ship was equipped with a torpedo-carrying DASH drone helicopter; its telescoping hangar and landing pad were positioned amidships aft of the mack.

[1] Knox performed search and rescue operations and provided evacuation, blockade, and surveillance support, when necessary, for the Pacific Fleet.

[1] [1] Knox appears in the original Hawaii Five-O (1968 TV series) season 8 episode Murder: Eyes Only.