USS LST-353 was an LST-1-class tank landing ship built for the United States Navy during World War II.

It was destroyed on 21 May 1944 when an explosion on its deck sparked the West Loch Disaster in Pearl Harbor naval base.

LST-353 was laid down on 15 July 1942 at the Charleston Navy Yard; launched on 12 October 1942; sponsored by Mrs. Estelle Lynette Cushman; and commissioned on 27 November 1942.

On 21 May 1944 she was sunk by internal explosion while moored in West Loch at Pearl Harbor, Hawaii and struck from the Naval Vessel Register on 18 July 1944.

[1] LST-353 earned three battle stars and the Navy Unit Commendation for World War II service.