USS LST-388 was a LST-1-class tank landing ship in the United States Navy during World War II.

During the North African occupation, Tunisian operations, she took part from 8 November 1942 to 9 July 1943.

She take part in the Sicilian occupation in Italy from 9 to 15 July 1943 and the Salerno landings from 9 to 21 September of the same year.

She participated in the Operation Crossroads the atomic bomb tests at Bikini Atoll in July 1946 and took on an important role as a general supply, provisions, hospital, and recreation.

LST-388 was struck from the Navy Register on 25 February 1947 and scrapped by Bethlehem Steel Company on 7 April 1948.