USS Lady Anne (SP-154) was an armed motor launch that served in the United States Navy as a patrol vessel from 1917 to 1919.

[2] Danna was sold to George P. Walker of Savannah, Georgia, on an unknown date and renamed Lady Anne.

She was enrolled in the Naval Coast Defense Reserve on 19 April 1917 and commissioned on 7 May 1917 at Charleston, South Carolina, as USS Lady Anne (SP-154).

She operated in the lower reaches of the Savannah River and along the Atlantic coast, inspecting merchant ships and sealing wireless radios.

[3] Lady Anne was decommissioned on 8 February 1919 and transferred to the Naval Overseas Transportation Service for non-commissioned use as a harbor patrol boat at Charleston.