USS Manchineel (AN-54/YN-73) was an Ailanthus-class net-laying ship which served with the U.S. Navy in the South Pacific Ocean during World War II.

Following shakedown off San Pedro, California, Manchineel departed 22 June for the South Pacific Ocean, arriving Pearl Harbor 1 July.

The net-laying ship then steamed for the Gilbert Islands, arriving Tarawa 23 May to pick up six pontoon barges for tow to Majuro.

On 10 October the ship departed for the U.S. West Coast via Pearl Harbor, arriving San Francisco, California, 3 November for mooring duty.

Manchineel decommissioned 11 March 1946, was stripped at Mare Island Naval Shipyard, and was struck from the Navy list 12 April.