After shakedown off Bermuda, Meredith departed Boston on 8 May 1944 as an escort in a convoy, arriving Plymouth, England, on the 27th.

On 6 June, Meredith gave gunfire support to the landing forces on Utah Beach.

Early in the morning of the following day, while patrolling the offshore waters as a screening vessel, she struck a mine.

[1] Severely damaged, with a loss of seven killed and over 50 wounded and missing, Meredith was towed to an anchorage in the Baie de la Seine to be salvaged.

However, on the morning of 9 June, her seams were further opened by an enemy bombing raid and shortly after she broke in two without warning and sank.