Escorting heavier ships en route, she transited the Panama Canal at mid-month and arrived at San Diego, California to report for duty in the 5th Amphibious Force on the 20th.

From 29 January, when Wotje was bombarded, until 5 February, when Remey struck an uncharted reef, she screened the transports and Carrier Division 22 (CarDiv 22) and provided gunfire support for the troops fighting for Kwajalein.

Following repairs, Remey completed an escort run for the USS Intrepid (CV-11) to San Francisco and back, then screened Bataan to Majuro.

Through June–July, she remained in the area, continuing her support for operations on Saipan and extending it to ground forces fighting on Tinian after 24 July.

Through the 24th, she continued her anti-small boat and antiaircraft patrols, then prepared to meet an enemy surface force reported standing toward the southern entrance to Surigao Strait.

Captain Jesse B. Coward, Commander, DesRon 54, divided his squadron into eastern and western groups to launch torpedo attacks against the Japanese as they steamed through the Strait toward defeat under the guns of the battleline.

Reports from the PT boats shadowing the Japanese were slow in coming, but at 0211 on 25 October, Remey, leading the eastern attack unit, moved south.

During November, she escorted reinforcements to Leyte, and in December joined CarDiv 22 for operations in the Sulu Sea in support of the landings on Mindoro.

On the 14th, she screened the sortie of TG 58.4, then sailed with that group as it struck enemy installations, shipping and troop concentrations on and around Kyūshū and the Ryūkyū Islands.

On 1 April, the group covered the assault on Okinawa's Hagushi beaches, then remained in the area until 11 May as ground forces pushed across Japan's last bastion protecting her home islands.

In commission, in reserve from January, Remey decommissioned on 10 December 1946 and was berthed at San Diego until ordered activated with the outbreak of hostilities in Korea.

Then, in the fall (September–December) of 1953, deployed briefly to European waters for joint operations with the Royal Navy followed by 6th Fleet exercises in the Mediterranean.

Remey remained in the western Atlantic through 1955 and, in the spring of 1956, as tension in the eastern Mediterranean from Cyprus to Suez, again heightened, rejoined the 6th Fleet.

On 6 November, Remey steamed back to the Mediterranean to assume patrol duties which continued until after Israeli forces withdrew from the Sinai Peninsula in late January 1957.

Returning in August, she participated in further ASW evaluation tests, then, in October, assumed duties as schoolship for the Destroyer Force's Afloat Engineering School.

During December of that year and January 1962, she cruised in the North Sea, returning to Newport in February and resuming reserve training duties at New York in August.