On 2 July 1943, she participated in the bombardment of the Vila Stanmore and Shortland Island areas in Kula Gulf, coming under the fire of enemy shore batteries.

During landings in the New Britain-New Ireland area, Renshaw dealt considerable damage to enemy airfield installations while coming under the fire of shore batteries.

On 13 March the ship was in the Empress Augusta Bay area where she bombarded enemy positions in the jungles east of the beachhead held by Allied forces.

At first assigned to the outer destroyer screen, she later closed the Tinian beach to provide star shell illumination and fire support for troops ashore who were undergoing a heavy counterattack.

In November 1944, while operating with a destroyer division bombarding enemy installations in the Ormoc Bay area and conducting anti-shipping sweeps in the waters westward of Leyte, Renshaw spotted Japanese submarine I-46[1] on the surface.

On 31 December 1944, Renshaw sortied with a task unit en route to screen a large transport formation assigned to land troops in the Lingayen Gulf area on 9 January 1945.

Renshaw then proceeded under her own power from the forward area to the Todd Pacific Shipyard in Tacoma, Washington, where permanent repairs were completed early in October 1945.

Subsequently, Renshaw served in the Pacific Proving Grounds, February to May 1954, during Operation Castle, rendering patrol and air control services for Joint Task Force 7.

This was followed by a short tour in the Far East from June to August 1954 where Renshaw rescued a British airman from the sea while acting as plane guard for the Royal Navy carrier HMS Warrior, and also participated in a hunter-killer exercise with a force composed of United States and Canadian ships.

She departed Pearl Harbor 8 April 1968 for WestPac where she provided escort services for the fast carrier attack forces on Yankee Station in the Tonkin Gulf.