On 28 April 2001 a US Coast Guard Law Enforcement Detachment (LEDET) assigned to Rodney M. Davis, with later assistance from the USCGC Active (based in Port Angeles, WA) made the largest cocaine seizure in maritime history when they boarded and seized the Belizean F/V Svesda Maru 1,500 miles (2,400 km) south of San Diego.

CARAT is an annual series of bilateral military training exercises designed to enhance cooperative working partnerships with several Southeast Asian nations.

The Rodney M. Davis Sailors' COMREL efforts included visits to local orphanages and maintenance/improvements at a library in the Cinco de Mayo district of the city.

Five more Rodney M. Davis sailors visited a local orphanage, Hogar Divino Nino, to spend time with infants and toddler orphans to give them some much needed human contact.

The two groups reassembled at another orphanage, Nutre Hogar, to hand out Spanish-language Disney movies to the children, which were part of a generous donation made through the Jacksonville, Florida, area office of the United Service Organizations (USO).

During the ship's three-day port visit, 21 members of the crew spent a day helping to improve Hogar Nuevo Pacto, a home for abused children in Panama City.

Rodney M. Davis sailors bought equipment to repaint the inside of the house, as well as groceries, new shower curtains, bed sheets, and light fixtures for the children's living areas.

Despite rainy weather outside, the crew spent the day productively inside, painting hallways and bedrooms, installing conveniences like toilet paper dispensers and toothbrush holders in the bathrooms, and replacing lights and correcting electrical safety problems.

The first maritime seizure of liquid cocaine occurred 25 April when the Rodney M. Davis located the fishing vessel Emperador from Ecuador in the Eastern Pacific.

The Coast Guard boarding team and crew of Rodney M. Davis transported the vessel to Guayaquil, Ecuador, for further examination by officials from the Drug Enforcement Administration and Ecuadorian authorities.

While on patrol in the Eastern Pacific Ocean, units assigned to the U.S. Navy's 4th Fleet and the U.S. Coast Guard intercepted a fishing vessel carrying more than 4 metric tons of cocaine, 5 December.

2, and U.S. Coast Guard Law Enforcement Detachment (LEDET) 106 intercepted the fishing vessel in an early morning interdiction, capturing nine suspected narcotics smugglers and the large cargo of cocaine with an estimated import value of $90 million.

Naval Forces Southern Command (NAVSO) and U.S. 4th Fleet, conducting counter illicit trafficking operations in support of JIATF-South, U.S. law enforcement and U.S. and participating nations' drug control policy.

TSC encompasses a robust strategy that includes military-to-military exchanges, multi-national exercises and training, diplomatic port visits, community relations activities and Project Handclasp distributions.

Aboard the Ecuadorian vessel the Rodney M. Davis's US Coast Guard Law enforcement detachment seized 1,562.5 kilos of cocaine in 62.5 bails.

[4] During the six-month deployment, the ship and crew of more than 200 Sailors, based at Naval Station Everett and assigned to Destroyer Squadron (DESRON) 9, conducted presence operations and theater security cooperation with partner nations in the Indo-Asia-Pacific region.