USS Simon Bolivar (SSBN-641), a Benjamin Franklin class fleet ballistic missile submarine, was the only ship of the United States Navy to be named for Simón Bolívar (1783–1830), the Venezuelan hero of the independence movements of the former Spanish colonies in South America.

In March 1966, Simon Bolivar's home port was changed to Charleston, South Carolina, where she was assigned to Submarine Squadron 18,[1] and minor deficiencies were corrected during a shipyard availability period.

Simon Bolivar departed Newport News on 12 May 1972 for post-overhaul shakedown operations and refresher training for her two crews, which lasted until 16 September 1972.

Simon Bolivar continued to make deterrent patrols, undergoing occasional refits at Naval Submarine Base Kings Bay Georgia, and was awarded the Battle "E" for Fiscal Year 1982.

Her scrapping via the U.S. Navy's Nuclear-Powered Ship-Submarine Recycling Program at Bremerton, Washington began on 1 October 1994 and was completed on 1 December 1995.