USS Sirius (AF-60) was a Alstede-class stores ship in service with the US Maritime Administration from 1943, and acquired by the United States Navy in 1956.

Her task was to carry stores, refrigerated items, and equipment to ships in the fleet, and to remote stations and staging areas.

Sirius was acquired by the U.S. Navy from the Maritime Administration on 18 May 1956 and commissioned on 12 January 1957 at San Francisco, California.

She supplied fleet units in Japan; Hong Kong, the Philippine Islands; Okinawa; and Taiwan.

Sirius was struck from the Navy List on 1 August 1965 and returned to the Maritime Administration, and sold to West Waterway Lumber Co., Seattle, Washington, on 13 April 1971.