USS Stettin was a 600-ton iron screw steamship, was built at Sunderland, England, in 1861 and later served as a gunboat in the United States Navy during the American Civil War.

The blockade runner had been attempting to slip into Charleston with saltpeter, lead, quinine, and assorted cargo from the Bahamas.

Condemned by the New York Prize Court, the steamer was purchased by the United States Navy on 4 September, and placed in commission as USS Stettin in November.

On 28 March 1863, she captured Memphis, and Ottawa shelled steamer Havelock as the blockade runner raced past them off Charleston on 11 June.

USS Stettin left the war zone late in the conflict and was decommissioned at the Boston Navy Yard on 6 April 1865.