Tills was assigned to Escort Division (CortDiv) 53 and conducted trials and shakedown off San Diego, California, before post-shakedown availability at Terminal Island.

On 16 October, the ship departed the west coast in the screen for Task Group (TG) 19.5, which included escort carriers Makin Island (CVE-93), Lunga Point (CVE-94), Salamaua (CVE-96), and Bismarck Sea (CVE-95).

In this, like the other operations staged from the Marshalls, the ship sailed easterly by day and westerly by night to a distance some 400 miles (640 km) east of Eniwetok.

Her patrolling of this stretch of the Pacific between the Hawaiian Islands and the Marshalls continued for 10 days before Tills returned to Pearl Harbor for availability alongside tender Alcor (AD-34).

The ship conducted post-availability exercises off Oahu before screening for Sangamon (CVE-26) in late February, while the escort carrier's planes carried out night flight training operations.

On 20 April, a typhoon upset the group's routine by grounding Corregidor's aircraft and pitching the small destroyer escorts in the heavy seas and 70-knot (130 km/h) winds.

En route to Okinawa, Tills sighted an abandoned Japanese patrol boat and sank the vessel with gunfire and depth charges.

Four days later, the destroyer escort returned to hunter-killer operations and maintained antisubmarine patrols on a continuous basis until making port at Ulithi for availability alongside repair ship Oahu (ARG-5).

While the destroyer escort was docked, in company with Torrance (AKA-76), Roberts (DE-749), and SS A. McKensie, airwaves brought the welcome news that Japan had surrendered on 15 August.

En route, the ship received word that a large transport plane had crashed into the sea off Oahu, and she was ordered to aid in the search for possible survivors.

Departing Coco Solo on 27 November, the destroyer escort proceeded to Hampton Roads for further availability in the Norfolk Navy Yard and initial preparations for decommissioning.

Refurbished by November, Tills was homeported at Miami and operated along the east coast from Boston, Massachusetts, to Panama and in the Caribbean, primarily training reservists.

On 1 May 1958, Tills' home port was moved to Boston, Massachusetts, shifting the locus of her operations northward to the northeastern coast of the United States and to the Canadian provinces of Nova Scotia and Newfoundland.

Following a six-week repair period at Newport, Rhode Island, and refresher training in Guantanamo Bay, Cuba, the ship operated out of her home port of Norfolk, Virginia.

Moving to Newport, Rhode Island, on 20 October 1963, the ship underwent a one-month tender availability during which she received new torpedo tubes which replaced her old ones and her K-guns.

After a tender availability alongside Grand Canyon (AD-28) from 22 March to 18 April, Tills returned to the Naval Reserve Training Center at South Portland, Maine, before getting underway for Boston on 13 June.