USS Upham (APD-99), ex-DE-283, was a United States Navy high-speed transport in commission from 1945 to 1946.

Too late to participate in combat, Upham exercised with an operational training unit in the Chesapeake Bay until 5 October 1945.

Shifting north to Hampton Roads, Virginia, Upham reached Norfolk, Virginia, in time for Navy Day festivities before moving to Jacksonville, Florida, to prepare for inactivation.

Decommissioned on 25 April 1946, Upham was placed in the Atlantic Reserve Fleet group on the St. Johns River at Green Cove Springs, Florida.

Sold to the government of Colombia in January 1962, Upham was converted for service as a floating power station.