USS William C. Miller (DE-259) was an Evarts-class destroyer escort constructed for the United States Navy during World War II.

After instruction at the Naval Training Station, Norfolk, Va., Miller was advanced to the rate of seaman 2d class on 21 February 1938 and joined Scouting Squadron 6, attached to the aircraft carrier USS Enterprise, on 30 September of that year.

Attacking Mitsubishi A6M Zero fighters riddled Dickinson's plane, but Miller, already wounded once, downed one and ultimately exhausted his ammunition in the defense of the aircraft until it had been set afire.

Dickinson managed to get out of the falling plane; but Miller, either dead or so severely wounded that he was unable to free himself from the aircraft-remained with it until it crashed into a cane field.

She returned to the west coast early in the fall but departed San Francisco on 19 October, bound for the Gilbert Islands and "Operation Galvanic".

Reaching Pearl Harbor on 30 December 1943, William C. Miller underwent upkeep alongside the destroyer tender Black Hawk (AD-9) and remained in Hawaiian waters into February 1944.

At 2120 on the evening of 13 July, a patrol plane sighted a Japanese submarine submerging some 78 miles from Rorpgattan Point, Saipan, and reported the enemy's position.

Accordingly, William C. Miller and the other members of a hunter-killer group – Gilmer (APD-11) carrying the officer in tactical command (OTC) – altered course and departed the screen for the transport area to track the submersible.

The ship soon recovered small pieces of cork insulating material; fractured wooden decking; and a fur-lined, Japanese seaman's cap.

I-6 was sunk in a collision with the freighter TOYOKAWA MARU on 16 June 1944 After the completion of the Tinian campaign, William C. Miller departed that island on 21 August in company with Indianapolis (CA-35).

William C. Miller returned to Eniwetok at the end of October and then shifted to Ulithi, in the Carolines, where she picked up Ulithi-to-Eniwetok Convoy Number 19 on 5 November.

Later that month, the destroyer escort headed home, via Ulithi, Eniwetok, and Pearl Harbor, and reached San Francisco, California, on 17 October.