[6] In April 2013, on two separate occasions, William P. Lawrence joined the Montcalm in rendering assistance to civilian mariners in distress while operating in the Gulf of Oman, as part of Combined Task Force 150.

[8] On 22 September 2013, a large wave hit a helicopter and pushed it into the Red Sea shortly after landing on William P. Lawrence, resulting in the death of two pilots.

The vessel was moving at flank speeds to relieve another escort ship in a defensive screen around Carrier Strike Group 3 in U.S. Central Command.

[9] On 10 May 2016, the US Navy reported that the ship sailed close to the Fiery Cross Reef, as part of a planned series of Freedom of navigation operations, (also referred to as FONOPs) in the area.

[13] As of October 2020[update], the ship was assigned to the United States Fourth Fleet supporting Joint Interagency Task Force South.