He has collaborated with acclaimed filmmakers such as Lars von Trier, Gus Van Sant, Werner Herzog, Rainer Werner Fassbinder, Walerian Borowczyk, Kleber Mendonça Filho, Dario Argento, Tom Shadyac, Charles Matton, Guy Maddin, Alexander Payne, and Paul Morrissey.

He has also become famous for his work with cult directors, including Rainer Werner Fassbinder, Walerian Borowczyk, Gus Van Sant, Christoph Schlingensief, and Dario Argento (whose classic Suspiria (1977) he was featured in).

He has appeared in almost all of Lars von Trier's films since 1987's Epidemic (with the exceptions of The Idiots, The Boss of it All, Antichrist and The House That Jack Built).

[12] Kier also appeared in the music videos for Korn's "Make Me Bad", Eve's "Let Me Blow Ya Mind", and "Die Schöne und das Biest" by defunct German band Rauhfaser.

He also voiced the Music Master in Justice League, Herbert Ziegler in The Batman, Ivan Bahn in Metropia, Professor Pericles in Scooby-Doo!

[14] Another documentary entitled Udo Kier - Dracula trash et dandy magnétique was released by Jobst Knigge (Germany, 2024, 52 min.)