Ueckermünde has a long and varied history, going back to its founding by Slavs, the Ukrani, mentioned in 934 by Widukind of Corvey.

In 1260 Barnim I, the duke of Pomerania, founded a monastery and the original trade center was awarded a town charter under Lübeck Law.

In 1276 the place was named Civitas, and in 1284 the Castrum Ukermunde, a fortress castle, was built by the Dukes of Pomerania.

On 5 September 1327 by the Treaty of Ueckermünde the Pomeranian dukes and the Brandenburgian margrave agreed on a formal peace.

In the course of the Great Northern War, after Russian and Saxon troops had occupied Stettin (now Szczecin) and Pomerania, Prussia made a payment of over four hundred thousand thalers for the provisional administration of the territory.

With the Peace of Stockholm, on 21 January (or 1 February) 1720 a payment of two million crowns was made to purchase Western Pomerania with Stettin, Usedom and Wollin.

[4] In the Gründerzeit in the second half of the 19th century, many new buildings that shape the old town including the market and St. Mary's Church were built.

At the end of the 19th century, an advanced medical facility St. Christopher's Hospital, known today as Ameos Clinic, was constructed.

At the time of national socialism, the ten to twelve remaining Jewish families were driven into exile or murdered.

The old town remained intact in GDR times but many buildings suffered major structural damage because of decades of lack of maintenance.

The area had been characterized by prefabricated buildings with a high housing vacancy, leading to partial restoration measures and restructuring processes.

The town, lying on the Oder Lagoon (Oderhaff, Stettiner Haff) is Germany's northeasternmost port city.

It is recognized by the state as a resort town, and it is home to the last palace of the Dukes of Pomerania still in existence on German soil.

It is Western Pomerania's biggest wooded area, and stretches from the northwest to the southeast over 50 km to the Polish town of Police (Pölitz in German).

After the war, large parts of the beach had very rough trenches, and the pier, used for mooring passenger ships and seaplanes, was destroyed.

In the following year the Hafftourist, an economic project of the local communities Ueckermünde, Mönkebude, Grambin and Vogelsang, was created to promote joint tourism ventures.

The Ueckermünder hospital gained notoriety in the wake of the so-called Action T4, with the large-scale murders of tens of thousands of helpless patients, many of them deemed "unworthy" children.

The following communities belong to Ueckermünde: Clockwise from the east are: Vogelsang-Warsin, Eggesin, Liepgarten, Lübs, Mönkebude and Grambin.

With the name „Wir von Hier“ a voters association with NPD-functionary Marko Müller ran for the local council.

Bundesstraße (Federal Highway) B 109 running between Anklam and Prenzlau passes 13 km to the town's west.