The uMkhanyakude District Municipality (Zulu: UMasipala wesiFunda sase uMkhanyakude) is the northernmost of the 11 districts of the KwaZulu-Natal province of South Africa.

It is a very rural district, the largest town being Mtubatuba in the south, with Hluhluwe, Mkuze, Jozini, Kwangwanase and Ingwavuma further to the north.

The municipality is named after the yellow-barked fever tree, literally meaning "seen from afar" in isiZulu.

It is one of the two most deprived districts in South Africa according to the District Health Barometer, in terms of unemployment rates, access to piped water and electricity, female-headed households with high numbers of children and low education levels.

uMkhanyakude is surrounded by: The district contains the following local municipalities: The following statistics are from the 2001 census.