The village is located in the southern part of the town, southwest of Oneonta.

The location of the village now called Unadilla was first settled about the same time by a group of Scots-Irish at the junction of the Ouleout Creek and the Susquehanna River.

Both villages were destroyed by the Continental Army in October 1778 because they were being used by Loyalists as a base for raiding frontier communities.

Shortly thereafter, Unadilla Village was again settled, and originally called "Wattles Ferry," It grew after it became an important stop for travel west: the Catskill Turnpike crossed the Susquehanna at Wattles Ferry, located in the eastern end of the village.

Eventually, the turnpikes were replaced in importance by the Albany and Susquehanna Railroad (later the Delaware and Hudson Railway).

[3] According to the United States Census Bureau, the village has a total area of 1.1 square miles (2.8 km2), all land.

28.1% of all households were made up of individuals, and 13.8% had someone living alone who was 65 years of age or older.