[9][13] Individuals who came from UTS took part in the formation of the Association of Theological Education in Southeast Asia in 1957[14] and the National Council of Churches in the Philippines in 1963.

[13] When various Protestant denominations from America came to the Philippines in the early 1900s, the missionaries started teaching Filipinos about the Bible and basic doctrines of Christianity.

On August 25, 1903, the Manila Bible Institute was initiated and has become an annual event to train church workers within a course of one month.

[13] The following year, the classes in Dagupan were transferred to Manila after the church acquired a property in Caloocan (then part of Rizal).

[18] With the shared vision of uniting various Protestant traditions, the Presbyterian and the Methodist Missions combined efforts to hold Bible classes for workers in 1905.

In early 1907, the leadership of the Ellinwood Bible School and the Florence Nicholson Seminary discussed the possible establishment of a united theological institution that would jointly train church workers from these two Protestant traditions.

The division of the classes into two different locations was found to be inconvenient, resulting in the decision to hold the sessions in the Ellinwood buildings and the Central Methodist Church.

The newly incorporated seminary did not have facilities of its own until a new building was erected at the corner of Taft Avenue and Herran Street (now Pedro Gil).

During the special meeting of the Board of Trustees on June 2, 1961, held in Baguio, it was approved that the seminary be assigned to a new location.

[19] The Board of Founders of the Nanking Theological Seminary provided the funds needed to buy a property.

Upon the request of the bishops of the UCCP and United Methodist Church in the Philippines in early 2001, the institution accepted and granted shelter to several families of Mangyans from Mindoro who had left their homes due to growing military operations in their localities.

The seminary has proclaimed its vicinity as a kanlungan ("refuge" in Filipino) and served as a sanctuary to the victims of forced displacement and oppression.

[23] Most of the facilities in Manila had been shared with the Philippine Christian College until the seminary moved to Dasmariñas, Cavite.

Since then, the seminary has occupied a small portion of the building along Taft Avenue, mainly for administrative and academic functions for post-graduate studies.

The CAP celebrates and emphasizes the Asian experience as theological education's situational, hermeneutical, missiological and pedagogical principle.

CAP includes the following concerns: Considering recommendations from the World Alliance of Reformed Churches and adopting the Revised CAP, the seminary has devised the Centennial Curriculum, in order to make the education contextual, holistic and responsive to the challenges and experiences of the Filipino people and become more relevant to Filipino life.