The Security Council also recognized that the renewed mandate of UNAMA is consistent with its resolutions 1662 (2006), 1746 (2007), 1806 (2008), 1868 (2009), 1917 (2010), 1974 (2011), 2041 (2012), 2096 (2013), 2145 (2014), 2210 (2015), 2274 (2016), 2344 (2017), 2405 (2018), 2460 (2019), 2489 (2019), 2543 (2020), 2596 (2021), 2626 (2022) The United Nations has been involved in the region since 1946 when Afghanistan joined the General Assembly.

The UNAMA opened a temporary remote office in Almaty, Kazakhstan in September 2021 to continue international humanitarian cooperation as result of the Taliban takeover.

This means that the Special Political Mission, all UN agencies, funds and programmes, work in a multidimensional and integrated manner to better assist Afghanistan according to nationally defined priorities.

UNAMA is headed by Special Representatives of the Secretary-General (SRSG) for Afghanistan, Roza Otunbayeva, who was appointed to the post in September 2022, replacing Deborah Lyons.

Nine Special Representatives have served in this capacity - Lakhdar Brahimi, (former Algerian Foreign Minister) served from October 2001 to January 2004, Jean Arnault held the post from February 2004 to February 2006, followed by Tom Koenigs from March 2006 to December 2007, Kai Eide from 2008 to 2010, Staffan di Mistura from 2010 to 2011, Ján Kubiš from 2012 to 2014, Nicholas Haysom from 2014 to 2016, Tadamichi Yamamoto from 2016 to 2020, and Deborah Lyons from March 2020 to June 2022.