This is a list of ambassadors of the United States to Kyrgyzstan.

Upon the breakup of the USSR, the Supreme Soviet of Kyrgyzstan declared itself independent of the Soviet Union on August 31, 1991, and renamed itself the Republic of Kyrgyzstan.

The United States recognized Kyrgyzstan on December 26, 1991.

An embassy was established in the capital, Bishkek, on February 1, 1992, with Edmund McWilliams as Chargé d'Affaires ad interim.

Relations between the United States and Kyrgyzstan have been continuous since that time.