The United States ambassador to Vietnam (Đại sứ Hoa Kỳ tại Việt Nam or formally Đại sứ đặc mệnh toàn quyền Hợp chúng quốc Hoa Kỳ tại Việt Nam, 'Ambassador extraordinary and plenipotentiary of the United States of America in Vietnam') is the chief American diplomat to the Socialist Republic of Vietnam.

The house used by the U.S. ambassador was designed by M. LaCollogne, Principal Architect and Chief of Civil Construction Service in Tonkin and built in 1921 by Indochina Public Property, part of the French colonial government, for Indochina Financial Governors who lived here until 1948.

When the French left South East Asia in 1954, Vietnamese government officials moved in.

Deputy Prime Minister Phan Kế Toại was the last occupant; at his death, the house became the headquarter of the Committee for Foreign Culture Exchange.

The residence was included in an exchange of property between the United States of America and the Socialist Republic of Vietnam in 1995.