US Post Office-Wellsville is a historic post office building located at Wellsville in Allegany County, New York.

It is one of a number of post offices in New York State designed by consulting architects Murphy & Olmsted to the Office of the Supervising Architect of the Treasury Department.

The interior includes two bas relief panels; one depicting the first League of Peace of the Iroquois tribes and the second depicting Mary Jemison, "White Woman of the Genesee."

[2] It was listed on the National Register of Historic Places in 1989.

This article about a historic property or district in Allegany County, New York, that is listed on the National Register of Historic Places, is a stub.