The United States Senate Committee on Health, Education, Labor and Pensions (HELP) generally considers matters relating to these issues.

Its jurisdiction also extends beyond these issues to include several more specific areas, as defined by Senate rules.

The act further expanded the committee's oversight to include the rehabilitation, health, and education of veterans.

[1] On July 25, 2024, the committee voted 16-4 to issue its first-ever subpoena, compelling the testimony of Steward Health Care's CEO Ralph de la Torre in relation to accusations of mismanagement of the health system.

[9] Tom Harkin, next in line by seniority, assumed the chairmanship on September 9, 2009, vacating his post as chairman of the Senate Agriculture Committee.

[10] Republican Mike Enzi of Wyoming continued to serve as Ranking Member.