Founded in 1974 with the support of then-President Luis Echeverria Alvarez, the institution aims to be closely linked to the social and human environment.

The University is established since its creation three units, which are located in Iztapalapa, Azcapotzalco and Xochimilco, with the idea of promoting decentralization and allow the full development of each.

Subsequently, it was decided that their internal organization would be composed of divisions and academic departments, creating a contrast with the Schools and Colleges of existing universities.

In turn, the Rector of the Azcapotzalco Unit was Dr. Juan Casillas García de León, which opened its doors 11 November 1974.

The April 26, 2005 the Academic College of the institution approved the creation of the Cuajimalpa campus, appointing in June of that year Dr. Fresán Magdalena Orozco as the first Rector.