[6][7][8] The creation of the university was a conservative response to a more-left wing direction being taken in Mexico in public higher education at the time.

On July 20, 1934, general Plutarco Elias Calles, a politician, revolutionary leader and former president, pronounced the speech known as "Grito de Guadalajara":[15] "Eternal enemies stalk her and try to make her triumphs nugatory.

The founders started dividing the foundational tasks such as renting houses for schools and colleges, set curricula, organizing the team of teachers and initiate enrollment, while incorporating studies of the National Autonomous University of Mexico (UNAM).

[citation needed] The first dean of the Autonomous University of the West was the lawyer Agustin Navarro Flores, under whose leadership the first faculties were organized.

; On May 15 were designated as Director and Secretary of the School of Medicine medical doctors Adolfo Esteban Saucedo and Cave Brambila; Dr. Agustin Hernandez was the first Director of Dentistry; the engineer Luis Ugarte was of Engineering and Professor Maria Villanueva assumed the leadership of the High School.

Manuel Calvillo, Director of Schools Incorporated, sent on behalf of Dr. Nabor Carrillo Flores, at that time Rector of the UNAM, the foundation stone of the University City, First Section, where there is now the Institute of Biological Sciences.

[27] In 1991, the Mexican federal government issued the 158th Agreement which granted the university full academic independence and the right to award degrees in all levels of education.

[28] The university sought and obtained support from other educational institutions in Mexico and in the international context, especially in Latin America and the United States.

In 1998 the Primary Care Mobile Unit (UMAP) was created which helped in the development of basic health within the concept of Medicine in the Community (PMC) program, the activities focused on community, education and welfare, allowing an adequate and varied exercise of medical education for the poor and sick.

The emergence of other newspapers, existing academic and student publications and expansion of the school, led to the creation of the Center of Communication University (CECUN) in 1977.

[48] The Nexus newspaper and the magazine Alma Mater, dedicated to university graduates and their families, and the academic publication Teaching, which is circulated in Latin America and is an instrument of international organizations such as GULERPE, CAMESA and IASEI, in the areas of health and news, are also published.

The university press publishes several dozen titles a year intended for educational, cultural or research purposes, with internal circulation.

The key features of UNICO are short courses that correspond according to the regulatory legal framework of the Secretaria de Educacion Publica (SEP).

and other athletic programs play their home games at the Estadio Tres de Marzo which is located in Zapopan, Jalisco.

By virtue of UAG ascending to the second level of Mexican football in 1973 and according to a ruling from the Federación Mexicana de Fútbol Asociación, new concrete stands were constructed on the sides of the pitch.

[50][51] The stadium once again went through renovation in order to accommodate the 1986 World Cup which brought the capacity to 30,015 people after new standing room areas were created.

In 1999, Estadio Tres de Marzo underwent its last major renovation which included improvements such as a new pitch and drainage system.

They gained promotion to Liga de Ascenso in their second season after beating La Piedad 4–0 under the management of Guillermo Sepulveda.