The project for the Catholic University "Nuestra Señora de la Asunción" was conceived by the Episcopal Conference of Paraguay and formalized by the Vatican's Holy See and Pope John XXIII as an entity of Superior Education at the end of the 1950s.

In September 1959, the Episcopal Conference reaffirmed its right to create universities, which was recognized by the 1940 National Constitution of Paraguay.

This legal recognition by the state was followed by the Resolution N°284 of July the 19th 1961, which established the relations between the Ministry of Education and Cult and the Catholic University Nuestra Señora de la Asunción.

The University Nuestra Señora de la Asunción has 6 Campuses and 2 Academic Units: • Institute for Appropriate Technology This is a Centre of capacitation and services.

Its objective is provide help the democratic process through the promotion and defence of human rights in the field of social law, political economy and education, specifically for the most vulnerable sectors of society.