Santa María La Antigua Catholic University (Spanish: Universidad Católica Santa María La Antigua, USMA) is a private university in Panama City, Panama.

As of 2021, it had 5,879 students, with more than 80 academic programs in both undergraduate and graduate degrees.

[1] Founded on May 27, 1965 as the first private university in Panama by Rev.

P. Benjamín Ayechu, the university began its academic activities in the Cathedral Park, in what was formerly the Archbishop's Palace, with 232 students, 9 majors and 21 professors.

[2] Since 1976, the university has moved to its current campus, on Avenida Ricardo J. Alfaro.