[7] The university was founded in 2008 with the aim of providing talented and working people with a challenging academic education, while at the same time enabling them to continue their professional career while studying.

University Isabella I was inaugurated through Act 3/2011 by the Parliament and the President of Castile and León in 2011,[8] when it was also formally authorized by the Kingdom of Spain to enrol official degree courses on Bachelor, Master and PhD level.

[12] The Isabel I University and the Fernán González Institution will collaborate on research on digital transformation linked to the humanities and social sciences signing a partnership on January 17, 2019.

This morning, the rector of the academic institution, Alberto Gómez Barahona, and the director of the Burgense Royal Academy of History and Fine Arts, Fernán González Institution,[13] José Manuel López Gómez, signed a specific collaboration agreement for both entities to jointly investigate on the technological and digital transformation in the field of education, humanities and economic and legal sciences.

The Foundation contributes to improving and consolidating the University's relations with its economic and social environment, collaborating in the search for the "first job" of the students, through the conclusion of agreements with companies and institutions.