The club was founded by students and professors from the Faculty of Exact Sciences and Technology of the Universidad Nacional de Tucumán on September 21, 1943.

Universitario played their matches in these pitches near the Parque 9 de Julio until 1958 when the government donated for a short term a field inside the Park.

In the year 1964, on the eve of the celebrations of the Bicentennial of the Battle of Tucumán, the club must return the land and settle in the university school of Physical Education (current headquarters of the Faculty of Physical Education or "FACDEF") In 1967, Uni bought the property on 4460th Lavalle Street in the Ojo de Agua area (since 1977, Barrio San Martín), but it continued to dispute the matches in the Park.

In 1976 the club must move permanently to the headquarters of Ojo de Agua due to the military coup that meant the closure of all the Faculties.

Universitario RC since its foundation won 17 Tucumán championships (from 1944 to 1999) and 7 Northwest Tournament (from its establishment in 1999 to the present):