University Center is a census-designated place (CDP) in Loudoun County, Virginia, United States.

The University Center CDP is in eastern Loudoun County, on the north side of Virginia State Route 7 (Harry Byrd Highway).

Via Route 7, it is 7 miles (11 km) northwest to Leesburg, the county seat, and 30 miles (48 km) southeast to Washington, D.C.

The community is bordered to the north by the Potomac River and to the east by Broad Run, its tributary.

Ashburn is to the south, across Route 7, and Montgomery County, Maryland, borders the CDP across the Potomac.