The University High School, (Spanish: Escuela Secundaria de la Universidad de Puerto Rico) commonly referred to by its initials "UHS", in San Juan, Puerto Rico is a college preparatory laboratory high school operated by the Faculty of Education of the University of Puerto Rico.

Located on the University of Puerto Rico, Río Piedras Campus, it provides education to approximately 514 students from 7th to 12th grade.

Its main building is a century-old art deco building located on Gándara Avenue and includes a three-story classroom annex designed in the 1970s by architect George McClintock, along with a roofed basketball court pavilion and school lunch cafeteria building (also designed by McClintock in the 1970s) shared with the UPR Elementary School.

UHS's faculty is composed of University of Puerto Rico professors.

Students who have fulfilled their general education requirements are allowed to take college-level courses at UPR's Río Piedras campus and all students are allowed to use the José M. Lázaro general library and other campus facilities.