The university offers education at undergraduate and postgraduate levels, which includes two doctorates.

On October 6, 1827, the Liberator Simon Bolivar formalized, thus was born the University of Magdalena and the Isthmus, because at that time Panama was part of Colombia.

In 1989, the university inaugurated the Health Campus, which moved the faculties of Medicine, Nursing, Dentistry and Pharmaceutical Chemistry.

The U of C has programs in the municipalities of Simiti, South Santa Rosa, Carmen de Bolivar, San Estanislao, Turbaco, Carmen de Bolivar, and San Marcos Magangué.

Master's degrees are offered in the fields of: Nursing, Mathematics, Chemistry, Physics, Education, Pharmaceutical Sciences, Environmental Sciences, Environmental Engineering, Biochemistry, Clinical Toxicology, Microbiology, Pharmacology, Clinical Epidemiology and Immunology, Philosophy.