It is part of the J. Hillis Miller Health Science Center, with facilities in Gainesville and Jacksonville, Florida.

In March 2009, the college received the largest donation in its history.

[3] U.S. News & World Report ranked the College of Medicine 36th out of 122 research-intensive medical schools in the U.S. in 2021.

[6] In December 2018 Expertscape recognized it as #4 in the world for expertise in Diabetes Mellitus Type 1.

[8] Admission to the University of Florida College of Medicine is considered to be highly competitive.