[3] Established in 1807 as the College of Medicine of Maryland,[4] it is the first public and the fifth oldest medical school in the United States.

UMB SOM's campus includes Davidge Hall, which was built in 1812, and is the oldest building in continuous use for medical education in the Northern Hemisphere.

[7] Its founding by Nathaniel Potter and John Beale Davidge was part of an influx of professionals to Baltimore and the rapid urban development that immediately followed the American Revolution.

[13] A group of physicians made several short-lived attempts at starting medical schools around the turn of the 19th century, and were finally successful in 1807 when the Maryland state legislature passed the Medical College Bill,[14] authorizing the formation the College of Medicine of Maryland.

It is listed on the National Register of Historic Places as the oldest building in continuous use for medical education in the United States.

[7] In the 1950s, the building was named after John Beale Davidge, one of the founders and the first dean of the College of Medicine of Maryland.

Investigators at IGS work on Disease Ontology research, the Data Analysis and Coordination Center (DACC) for HMP, and other grants.

The IGH develops new and improved ways of diagnosing, preventing, treating, controlling and eradicating diseases of global impact.

[24] After the study gained media publicity, research funding was made available and a new building was constructed on the north side of the hospital grounds to house MPRC, a division of the department of Psychiatry of the University of Maryland School of Medicine.