[3] Over the centuries the University of Messina has been a centre of attraction for esteemed scholars and historical figures, such as Giovanni Pascoli, Marcello Malpighi, Gaetano Salvemini and Vittorio Emanuele Orlando.

The Faculty of Medicine is held in the main hospital of the city Policlinico G. Martino, situated in the southern area of Messina.

The Faculties of Veterinary Medicine, Pharmacy and Humanities are established in the Polo Annunziata facility, which is also the Sport Centre of the University.

It reached high levels, featuring top professors including Giovanni Alfonso Borelli, Pietro Castelli, Giovan Battista Cortesi, Carlo Fracassati, Giacomo Gallo, Mario Giurba, Marcello Malpighi and Francesco Maurolico.

Between 1919 and 1920 all the courses of the Faculty of Medicine were carried out thanks to the local institutions, which approved the establishment of a consortium managing the Civil Hospital where clinics had a temporary location.