The university's East Campus houses athletic facilities including Maestri Field and the UNO Lakefront Arena.

For its first five years, it was reckoned as an offsite department of the main campus in Baton Rouge, and as such its chief administrative officer was originally called a dean (1958–1961), then a vice president in charge (1961–1962).

To signify that it was now a co-equal institution with LSU, its chief executive's title was changed from "vice president in charge" to "chancellor."

After a decade of growth, the LSU Board of Supervisors approved a name change to the current "University of New Orleans."

The main campus is on relatively high ground, so the damage was caused mostly by winds, rain-driven-water, and human activity during the storm.

A levee breach on the London Avenue Canal occurred just a few blocks south of the main campus and caused the flooding of the first floor of the Bienville Hall dormitories, the Lafitte Village couples apartments, and the Engineering Building.

UNO was the first of the large, damaged universities in New Orleans to re-open, albeit virtually, by using web-based courses starting in October 2005.

Partially due to a large portion of UNO's non-traditional student base seeking education at non-traditional online universities, a failure to truly have in-person classes for traditional students in the years following COVID, and subsequent hurricanes the years following, UNO's enrollment hit record lows, close to its post-Katrina numbers.

Because of this, less than a year after her appointment to the position, President Kathy Johnson laid off numerous employees and shrunk budgets by over 15% during the summer of 2024.

Kirschman Hall, the newest lecture building on campus and home of the College of Business Administration, features a large atrium in the center with a few satellite hallways connecting to it.

This location includes offices of Enrollment, Orientation, the Bursar, Financial Aid, and Academic Advising.

The second floor is home to quiet computers, additional group study rooms, periodicals, the Women's Center, and the UNO Press.

After being used as office space while campus was being reconfigured after Katrina, the main residential section of the building finally closed down in 2010.

Once the cafeteria and amenities for on campus housing, it is now home to the Facility Services Workshop, and some storage for the Engineering Building.

The university's dining services are currently managed by Chartwells Higher Ed, a branch of Compass Group.

They manage all dining locations on campus including the university's buffet-styled cafeteria is known as the Food Hall at the Galley.

Moe's Southwest Grill and the Sandbar at the Cove are under temporary closure due to low student enrollment.

[27] The University of New Orleans currently has 14 varsity sports teams, and is a Division I member of the NCAA (National Collegiate Athletic Association), competing in the Southland Conference.

[28] On February 1, 2011, Provost Joe King submitted the Division II proposal to the LSU Board of Supervisors.

[30] On March 9, 2012, President Peter J. Fos announced that UNO plans to remain a member of NCAA Division I, with potential homes being the Sun Belt or Southland Conference.