The Upper East Side Historic District is a landmarked historic district on the Upper East Side of New York City's borough of Manhattan, first designated by the city in 1981.

[2] It was listed on the National Register of Historic Places in 1984.

[5] The district is home to a number of buildings individually listed on the National Register, including the Gertrude Rhinelander Waldo Mansion and the Sara Delano Roosevelt Memorial House,[1] as well as edifices that are more recent additions like the Edmond J. Safra Synagogue — a 2003 building designed in an "artful synthesis of the composition, details and material palette of the Beaux-Arts style," to complement the historic buildings that surround it.

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